Á¦  ¸ñ :   methylation,thÁ¶Àý

http://www.herbaltransitions.com/methylation.html#factorsdisturbingmethylation

https://www.beyondmthfr.com/


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MTHFR Gene Polymorphisms Causes Undermethylation or Overmethylation

**Àá±ñ!!>>folic acid(ÀΰøÇÕ¼ºº¸ÃæÁ¦--B9....SIBO/Dysdiosis¶§¿¡ ¼¼±ÕÀÌ ¸¸µé¾î³»´Â B9Àº °ÅÀÇ ¸ðµÎ folic acidÇüÅÂÀÓ)´Â folate(È°¼ºÇü...½Ä¹°·Î ¼·Ãë ÇüÅÂ...¿ä¸®Áß 50-75% Æı«µÊ...¼ÒÀå¿¡¼­ Èí¼ö·®µµ Àû´Ù..¸ÞÄ¥±â °ø±Þ/DNA¼Õ»óº¹±¸ ±â´É)·Î º¯È¯µÇ´Â ¾çÀº ¼Ò·®¿¡ ºÒ°úÇÔ.. º¸ÃæÁ¦ folic acid ¸¸ ´ë·®¼·Ãë½Ã, ¶Ç´Â (SIBO¶§ ·¡folate´Â Á¤»óÀ̰ųª »ó½Â)Àå³»¼¼±ÕÁõ½Ä¿¡ ÀÇÇØ folic acid ´ë·®»ý»ê + (¼¼±ÕÀÌ »ç¿ë) B12°áÇ̽Ã(Àú¸ÞÆ¿È­°¡ ´õ ¾ÇÈ­!!), NK¼¼Æ÷¸¦ ¹«·ÂÈ­½ÃÄѼ­ ¹ß¾ÏÀ²°ú´Â »ó°ü ¾ø¾úÀ¸³ª ¾ÏȯÀÚ´Â ¾ÇÈ­µÉ ¼ö ÀÖÀ½..ÇÑÆí, polymorphismÀ̶õ (¸¸´ÉŰó·³,,,¶§·Î´Â ÀÌ ¸ð¾çÀ¸·Î ¶§·Î´Â Àú ¸ð¾çÀ¸·Î) »ç¶÷¸¶´Ù ¼­·Î ´Ù¸¥ ÇüÅ·Π±× °á°ú°¡ ³ªÅ¸³¯ ¼ö ÀÖ´Ù´Â ¸»(´ÙÇü¼º)..Áï, Àú¸ÞÆ¿È­¿¡¼­µµ °æµµ/Áߵ·Î, ¶Ç´Â Àú¸ÞÆ¿È­»Ó ¾Æ´Ï¶ó ½ÉÁö¾î °í¸ÞÆ¿È­ °æÇâµµ À¯¹ßÇÒ ¼ö ÀÖ´Ù Çؼ®Çصµ ¹«¹æÇÒ °Í.

(MTHFR)À¯ÀüÀÚ´Â MTHFR È¿¼ÒÀÇ »ý¼ºÀ» ÁÖ°ü. MTHFR´Â ¿±»êÀÇ ÇüŸ¦ (ºñÈ°¼ºÇüÀÎ folic acid¸¦ È°¼ºÇüÀÎ folate·Î) º¯È­½ÃÅ°°í, È£¸ð½Ã½ºÆ¾À» ´ë´Ù¼ö ´Ü¹éÁúÀÇ ÁÖ¿ä ±¸¼º¿ä¼ÒÀÎ ¸ÞƼ¿À´ÑÀ¸·Î º¯È¯½ÃÅ°´Â °úÁ¤(ÀÌ°ÍÀÌ ¸ÞÄ¡¿À´Ñ »çÀÌŬ, ¶Ç´Â Æ¿·¹À̼ǻçÀÌŬÀ̶óÇÔ)¿¡ °ü¿©....MTHFR °Ë»ç´Â MTHFR À¯ÀüÀÚ¿¡¼­ »ó´ëÀûÀ¸·Î ÈçÇÑ µÎ ¿°±âº¯ÀÌ(´ÜÀÏ¿°±â´ÙÇü¼º, SNP)ÀÎ C677T ¹× A1298C¸¦ °ËÃâ. À̵é SNP´Â DNAÀÇ º¯È­(µ¹¿¬º¯ÀÌ)¸¦ À¯¹ßÇÏ°í, ((Àú¸ÞÆ¿È­¸¦ À¯¹ßÇÏ´Â °æ¿ì´Â...À¯ÀüÀÚ ÀÚä°áÇÕ +Àå³»¼¼±Õ Áõ½ÄÀ¸·Î ÀÎÇÑ °æ¿ì°¡ ´ëºÎºÐ??...ÇÑÆí °í¸ÞÆ¿È­´Â Àå³»¼¼±Õ/Áø±Õ Áß°£´ë»ç»ê¹° Áõ°¡ÀÚü¿¡ ÀÇÇÏÁö ¾Ê³ª »ý°¢ÇÏ´Â °Ô ÇÕ¸®Àû..))Á¶±â½ÉÇ÷°üÁúȯ, Ç÷ÀüÁõ ¹× ³úÁ¹ÁßÀÇ À§Çèµµ¸¦ Áõ°¡½ÃÅ°´Â È£¸ð½Ã½ºÆ¾ ³óµµÀÇ Áõ°¡¿Í °ü·ÃµÇ¾î ÀÖ´Ù. ºÏ¹Ì Àα¸ÀÇ ¾à 10-12%°¡ C677TÀÇ µ¿ÇüÁ¢ÇÕü. ºóµµ¿¡¼­ ÀÎÁ¾º° Â÷ÀÌ°¡ Àִµ¥, ÁöÁßÇØ°è¿¡¼­ °¡Àå ³ô°í ¾ÆÇÁ¸®Ä«°è¿¡¼­ °¡Àå ³·´Ù....C677T ¿°±âº¯ÀÌ´Â MTHFR È¿¼Ò¿¡¼­ ´ú È°¼ºÈ­µÈ ÇüŸ¦ À¯¹ß. MTHFR C677T À¯ÀüÀÚµ¹¿¬º¯À̸¦ µÎ °³(µ¿ÇüÁ¢ÇÕü), ¶Ç´Â MTHFR C677T°ú A1298C¸¦ °¢°¢ ÇÑ °³¾¿(º¹ÇÕÀÌÇüÁ¢ÇÕü) °¡Áø °æ¿ì, MTHFR È¿¼Ò È°¼ºµµÀÇ °¨¼Ò´Â È£¸ð½Ã½ºÆ¾-¸ÞƼ¿À´Ñ Àüȯ °úÁ¤À» ´ÊÃß¾î Ç÷Áß È£¸ð½Ã½ºÆ¾ ³óµµ¸¦ Áõ°¡½ÃÅ°°Ô µÈ´Ù....È£¸ð½Ã½ºÆ¾Àº ¶§·Î °æµµ¿¡¼­ Áߵ±îÁö Áõ°¡µÇÁö¸¸, MTHFR È¿¼Ò È°¼ºµµ ¾ç¿¡ µû¶ó »ç¶÷¸¶´Ù Â÷ÀÌ°¡ ÀÖ°í,. È£¸ð½Ã½ºÆ¾ Áõ°¡´Â ȯÀÚ°¡ ¿±»ê °áÇÌÀÏ ¶§ ¾ÇÈ­....ÀϺΠ¿¬±¸ °á°ú´Â °í³óµµÀÇ Ç÷Áß È£¸ð½Ã½ºÆ¾ÀÌ Ç÷°üº®À» ¼Õ»ó½ÃÅ°°í ÇöóÅ©(Á׻󵿸ưæÈ­) ¹× ºÎÀûÀýÇÑ Ç÷Àü Çü¼ºÀ» ÃËÁø½ÃÅ´À¸·Î½á ½ÉÇ÷°üÁúȯ À§Çèµµ¸¦ Áõ°¡½ÃÅ´À» ½Ã»çÇÏ°í ÀÖÁö¸¸ È£¸ð½Ã½ºÆ¾ ³óµµ¿Í ½ÉÇ÷°üÁúȯ ¶Ç´Â Ç÷Àü À§ÇèµµÀÇ Á÷Á¢Àû ¿¬°áÀÌ Áõ¸íµÇÁö´Â ¾Ê¾Ò´Ù. 

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**¿±»êÀº ³ú³»¿¡¼­ ¸ÞÄ¥±×·ì°ø¿©Àڷμ­ ÀӽŞÆÀÇ ³úÀÇ ¹ß´Þ ÃËÁø, È£¸ð½Ã½ºÅ×Àλý¼º¾ïÁ¦, ¼¼·ÎÅä´Ñ(¿ì¿ïÁõ ÁøÁ¤ = Çູ°¨ °í¾ç ...Àϱ¤¿å½Ã ´õ Áõ°¡), µµÆĹÎ-³ë¸£¿¡Çdz×ÇÁ¸° »ý»êÀ» ÃËÁø ..... https://lifecenter.tistory.com/28


[¼ÒÀå³»¼¼±Õ°ú´ÙÁõ½ÄSIBO]

Ç×»ýÁ¦ ³²¿ë ¹× PPIÀå±âº¹¿ë, chronic leaky gut, ileocecal valve dysfunction, and chronic stressÀ¸·Î ÀÎÇÑ SIBOµî Àå³»¼¼±ÕÁõ½Ä½Ã »ó½ÂÇÏ´Â ´ë»çºÒÈ°¼º folic acidÀº MTHFRÀ¯ÀüÀÚ ¹× ´Ù¸¥ À¯ÀüÀÚÀÇ È°¼ºÀå¾Ö°¡ À¯¹ß( excess folic acid, low b12 and a host other malnutrition/methylation issues.)µÇ¾î ÀÖ´Â °æ¿ì ¸ÞÆ¿·¹ÀÌ¼Ç ÀÌ»ó ÃÊ·¡ÇÏ°Ô µÉ °Í

***Common health issues associated with SIBO include:

Low B12(MCV : È°¼ºÇü B6, B12¸¦ ¹Ý¿µÇÔ...MCV>90)== High Folic Acid== Low Iron<ÈѸ®Æ¾ 60ÀÌÇÏ·Î ÀúÇÏ>, Low Vitamin A, D, E, and K<ºñŸ¹ÎDÀúÇÏ>== Low Omega 3’s and other fatty acids<ÇʼöÁö¹æ»ê ÀúÇÏ>

Difficulty gaining weight / failure to thrive üÁßÀúÇÏ ¼ºÀåÁö¿¬==Gas ÀæÀº ¹æ±Í==Diarrhea¼³»çºó¹ß==Bloating Æظ¸==Abdominal Pain º¹Åë==Food in stool ¼ÒÈ­ ¾ÈµÈ º¯==Fat in stool Áö¹æº¯==GB disease ´ã³¶Áúȯ º´¹ß==Acid reflux  À§½Äµµ¿ª·ù==Malabsorption Èí¼öÀå¾Ö==Difficuly losing weight / obesity üÁßÁ¶Àý °ï¶õ==and much more…

There are a number of theories regarding the causes of overmethylation as well as undermethylation. The most obvious cause is that of MTHFR genetic polymorphisms. If you possess a polymorphism of the MTHFR gene, this may be directly associated with poor methylation or highly efficient methylation. Fortunately you can detect whether you have a mutation of the MTHFR gene by getting a simple blood test.

MTHFR is an acronym for “Methylenetetrahydrofolate Reductase.” MTHFR is an enzyme and the MTHFR gene is necessary for the creation of the enzyme which regulates the methyl cycle. When the gene is considered abnormal, the methyl cycle may function abnormally. There are a variety of possible mutations that may occur to the MTHFR gene as well as its nucleotides.

If the gene’s nucleotide is abnormal, it’s called a SNP (Single Nucleotide Polymorphism). With the MTHFR gene, there are a variety of nucleotide polymorphisms (SNPs) that may occur, some are considered heterozygous (on one strand of DNA) while others can be homozygous (on both strands of DNA). Upon diagnosis, a professional will be able to explain whether you have homozygous or heterozygous MTHFR and the specific SNP location.

Source: http://www.ncbi.nlm.nih.gov/books/NBK6561/


Undermethylation vs. Overmethylation: Causes, Symptoms, Treatments

While there are a number of potential factors that may cause mental illness, one that many people don’t consider is that of methylation. It is believed that genetic mutations may lead to abnormalities in the methylation process. The methylation cycle is a specific biochemical pathway that is responsible for influencing a variety of critical biological processes including: the immune system, DNA maintenance, production of energy, and detoxification. 

During the methylation process, neurotransmitters are created, giving rise to certain emotional states. If there is problems with the methylation process, it is speculated that a number of different psychiatric symptoms may arise. These speculative symptoms are thought to be specifically correlated with whether someone is considered to be stuck in a state of “overmethylation” vs. “undermethylation.”

Undermethylation vs. Overmethylation

There isn’t anything wrong with being overmethylated nor undermethylated, but it may cause some sort of mental distress. Too much methyl (overmethylation) results in a unique set of symptoms that are different than those resulting from too little methyl (undermethylation). While undermethylation is generally considered less problematic than overmethylation, you may want to consider “methylation” and its potential to cause mental illness.

Undermethylation (Histadelia): Too little methyl (a carbon group with three hydrogen atoms). Essentially they have low levels of SAM-e, which donates methyl. This can lead to perfectionism, high accomplishment, and high achievement. Now why would this be problematic? 15-20% of these people experience problems as a result of the undermethylation. This can lead to low levels of serotonin, making them susceptible to depression 

Overmethylation (Histapenia): Too much methyl (a carbon group with three hydrogen atoms). It is very active in the brain, and too much leads to “too much of a good thing.” This causes an overproduction of serotonin, norepinephrine, and dopamine in the brain.  In many cases, high serotonin levels can cause psychological problems including reduced motivation, reduced libido, weight gain, and confusion.


Biochemistry of Overmethylation

Overmethylation is the polar opposite of undermethylation. If you are overmethylated, you will likely have elevated levels of serotonin, low levels of histamine, and likely a low count of absolute basophils. Additionally you may discover high levels of copper, but low presence of zinc and histamine throughout the body.

High copper***(Ç×»ó): Abnormally high levels of copper are generally present among those who exhibit overmethylation.

Low basophil count: In cases of overmethylation, basophil count tends to be depressed, meaning theres less likelihood of an allergic reaction.

Low histamine***: Overmethylation results in the reduction of histamine, making it completely unnecessary to use an over-the-counter antihistamine.

Low zinc: Another common finding among those who are overmethylators is low levels of zinc.

Overmethylation Symptoms

Below is a list of possible symptoms that you may experience during overmethylation. Understand that overmethylation will not necessarily cause every single symptom on the list and that severity of each symptom is highly subject to individual variation.

ADHD : Those who are overmethylators may have attention deficits and may have been previously diagnosed with ADHD.--..ADHDÄ¡·áÁ¦´Â º»·¡ µµÆĹÎ(¼ºÃ뵿±â Áõ°­)°ú NE(ÁýÁß·Â Áõ°­)»ó½Â½Ãų ¸ñÀûÀ¸·Î »ç¿ë--#¸®Å»¸°¿ÜÀÇ ADHDÄ¡·áÁ¦ ....ÇãºêƼ ( chamomile, spearmint, lemon grass)//Ginkgo Biloba+¸®Å»¸°//¹ÙÄÚÆÄ//Gotu Kola//Green Oats//Ginseng

Anxiety  ºÒ¾È, Áö³ªÄ¡¸é °øȲ: In some cases, the overmethylation can lead to increased levels of anxiety and susceptibility to panic attacks.

Artistic ¿¹¼úÀû ÃëÇâ: Some sources have suggested a link between artistic and musical pursuits and overmethylation. Whether this is accurate is subject to debate.

Depression ¿ì¿ï/µ¿±â°á¿©·Î ÀÎÇÑ Çо÷¼ºÃëÀúÇÏ: Those with overmethylation may become depressed as a result of high levels of serotonin, lack of motivation, and accomplishment.

Dry skin °ÇÁ¶ ÇǺÎ: It has also been speculated that in those who are overmethylated tend to be more susceptible to bouts of dry skin.

Food sensitivities À½½Ä ¹× È­Çй°Áú÷°¡Á¦ °ú¹Î/³ú¾Ë·¹¸£±â: If you are an overmethylator, you may notice that you are highly sensitive to certain foods and/or chemicals.

Frustration ±äÀå/°¥µî..Ç×»ó ´Þ·Áµé¾î ½Î¿ïÁغñ µÈµí.: Another sign among overmethylators is rampant frustration or becoming easily frustrated in seemingly benign situations.

High pain threshold ÇǾî½Ì/¹®½Å ¹Ýº¹..ÅëÁõ¿ªÄ¡ ³ô´Ù: Unlike those who are poor methylators, overmethylation is associated with a higher pain tolerance.

Low libido ¼º¿å°¨Åð: Another symptom of overmethylation is that of a decreased sex drive. They may be considerably less interested in sex than average.

Low motivation °æÀï½É/µ¿±â-¼ºÃë °áÇÌ: The general tendency among overmethylators is that of deficient achievement in workplace or competitive settings. This is often a direct result of the motivational deficit that may be a byproduct of overmethylation.

Nervousness Â¥Áõ/½Å°æÁúÀû..¿¹¹Î..ºÒ¾ÈÀ¸·Î ÀÌÇà: This ties into the generalized anxiety that a person may experience as a result of the overmethylation.

Obsessions °­¹Ú: Some have suggested that individuals with overmethylation may demonstrate clear obsessions, but they aren’t usually accompanied by compulsions.Ã浿 ---UMÀÇ °æ¿ì ´õ ¸¹´Ù.

Overweight üÁß°ú´Ù: Those who are overmethylated may be more likely to pack on weight in part due to motivational deficits and depression.

Paranoia ¸Á»ó, ȯû: Among those who are strongly affected by overmethylation, paranoid thoughts, and possibly auditory hallucinations may emerge.

Restless legs ÇÏÁöºÒ¾ÈÁõ: Another possible symptom that you may experience if you’re dealing with too much methylation is restless legs.

Self-imposed isolation°í¸³ÀÚÃÊ-ºÒ¾È/¿ì¿ï·Î ÀÎÇÔ: Those who isolate themselves from others may do so in part as a result of depression and or anxiety from overmethylation.

Self-harmÀÚÇÐ: Researchers believe that among those who commit acts of self-harm and mutilation, overmethylation tends to occur.

Sleep disorders: Those with sleep problems may be more likely to have overmethylation.

Overmethylation Treatment

If you are dealing with overmethylation, many experts will recommend a specific supplement regimen over the course of 3 to 6 months. Some believe that it is easier to offset the effects of overmethylation than undermethylation. While you probably won’t notice major benefit overnight, you may start to feel gradually better over the course of several months.

To properly cope with overmethylation, it is recommended to work with a professional to construct a specific regimen of supplements. These supplements work to correct nutritional imbalances and should improve symptoms of the condition.

Supplements for Overmethylation

Working with a professional will help you come up with a supplement regimen that effectively offsets the overmethylation. The goal is to gradually reduce the amount of methylation that occurs with targeted nutritional interventions. Below are some supplements that someone may take if they are overmethylated.

Omega-3 fatty acids

DMAE : NE ·Î ÀÎÇÑ Áõ»óÀ» Á¶ÀýÇÏ´Â Ach»ý¼º ÃËÁø

Folic Acid (Folate) =B9/Niacinamide =B3/Vitamin B6

Vitamin C :: ±¸¸® µ¶¼º Â÷´Ü+ Epi-->¾Æµå·¹³ëÅ©·Ò Â÷´Ü(Á¤½ÅÁõ»ó ¿ÏÈ­)

Vitamin E

Zinc : ±¸¸® µ¶¼º Â÷´Ü

Medication Outcomes

If you are taking a medication and have a mutation of MTHFR that leads to overmethylation, below are some likely reactions.

Antihistamines: Since you already have low levels of histamine, you are going to respond poorly to any antihistamine drug. People who are overmethylated tend to have less allergic responses than usual as a result of the low endogenous histamine.

Benzodiazepines(xanax, gabapentin): Favorable responses have been noted among those with overmethylation to taking benzodiazepines.

Lithium: The mood stabilizing agent Lithium has also been thought to yield noticeable improvement among those who are overmethylated.

Oestrogen therapy: Should you engage in oestrogen therapy as an overmethylator, you are likely to experience an adverse reaction.

SAM-e: This supplement should be avoided by any individual that is dealing with overmethylation. Adverse reactions are likely to occur as this will further increase methylation.

SSRIs: In general, people who are overmethylated already have high levels of serotonin and don’t require an SSRI. Further increasing serotonin levels may be problematic and may yield unwanted side effects or adverse reactions.


Biochemistry of Undermethylation

The undermethylation can lead to a number of deficiencies in nutrients throughout the body. Some researchers believe that if a person is a poor methylator, they are likely to have high levels of histamine, reduced zinc, and a high basophil count.

High histamine: It is thought that a metabolic imbalance occurs when a person isn’t capable of sufficient methylation, leading to abnormally high histamine (e.g. 70 ng/ml).

Low plasma zinc: Some individuals who are chronically undermethylated tend to have zinc deficiencies.

Low serum copper***(Á¤»óÀϼöµµ ³ôÀ»¼öµµ ÀÖÀ½): Those with poor methylation ability tend to have low levels of copper.

High Basophil count: This is often detected in blood tests and is associated with infections and allergic reactions. If levels exceed 50 cells/cu mm, there’s a better chance of undermethylation.

High homocysteine(???)***: The greater the degree of undermethylation, the higher you can expect your homocysteine levels.(B12-¿±»êºÎÁ·½Ã´Â È£¸ð½Ã½ºÅ×Àο¡¼­ ¸ÞÄ¡¿À´ÑÀ¸·ÎÀÇ Àüȯ °¨¼Ò....B6ºÎÁ·½Ã´Â È£¸ð½Ã½ºÅ×Àο¡¼­ ½Ã½ºÅ¸Ä¡¿ÂÀ¸·ÎÀÇ Àüȯ Â÷´ÜµÊ...OMÀ̳ª UM¿¡¼­ ¸ðµÎ »ó½Â °¡´É??)

High heavy metals***: Proper methylation is thought to help detoxify the body of heavy metals and toxins. If a person is undermethylated, some speculate that they may have increased build-up of heavy metals.

Undermethylation Symptoms

Keep in mind that if you are suffering from undermethylation, you may not experience every symptom on this list. There are different genetic polymorphisms of the MTHFR gene as well as other factors that may dictate your experience. Below is a collective list of symptoms that people with undermethylation tend to exhibit.

Addictions ¾à¹°Áßµ¶ °æÇâ: Those who are considered undermethylators may be more likely to battle addictions and/or have addictive personalities.

Competitive °æÀï½É¸®: It is believed that many undermethylators are extremely competitive in sports, business, and other facets of life. Competition is a notable signal that a person may not have a sufficient methylation process.

Concentrative endurance ±ä ½Ã°£ ÁýÁß °á¿©/´Ü½Ã°£¿¡ ¼îºÎ ¼±È£: Some individuals who are suffering from undermethylation may have a difficult time maintaining focus for prolonged periods of time. In other words, their concentration ability may wane quicker than average.

Delusions ȯ°¢..Çö½Ç°¨ °á¿© À¯¹ß: Certain individuals that fall into the undermethylation diagnosis may experience delusions or beliefs that aren’t based in reality. While these generally are not severe, then can interfere with the accuracy of a person’s perception of reality.

Headaches µÎÅëºó¹ß: Some researchers believe that undermethylation may cause physical symptoms such as headaches.

High achievement ¼ºÃë ¼ö¿ù: One characteristic (rather than symptom) of people with low levels of methylation is that of accomplishment and achievement. Many individuals considered top athletes, CEOs, and professionals may be fueled in part by undermethylation.

High libido ¼º¿å°úÀ×: A person may be highly interested in sex and/or have a higher than average “drive” compared to others.

Obsessive compulsive °­¹ÚÃ浿: Undermethylation may provoke symptoms of OCD or other obsessive tendencies. In fact, someone may actually get diagnosed with obsessive-compulsive disorder as a result of their methylation deficiency.

Oppositional defiance ¹Ý´ëµµÀüÀå¾Ö: Another common finding is that those displaying signs of oppositional defiant disorder (ODD) tend to also have undermethylation. While this isn’t a very common diagnosis, it is thought to be related to undermethylation.

Inner tension: While a person who is an undermethylator may appear to exhibit a calm demeanor, they may be filled with inner tension.

Low pain tolerance ÅëÁõ¿ªÄ¡ ÀúÇÏ: Individuals with undermethylation tend to have a poor tolerance to any sort of pain.

Perfectionism ¿Ïº®ÁÖÀÇ°æÇâ: Another trait of undermethylators is that of perfectionism. They aren’t satisfied unless tasks are completed in accordance to their specific methodology. They may be intolerant to less-than-perfect outcomes.

Phobias °øÆ÷Áõ: Certain phobias or irrational fears may be caused in part by undermethylation.

Ritualistic behavior: Those who are undermethylated may engaged in ritualistic behavior with rigid schedules. They may have specific daily rituals to which they must adhere.

Seasonal allergies °èÀýÀû ¾Ë·¹¸£±â: It has also been suggested that allergies may be stronger among undermethylators, particularly during seasonal transitions. This may be related to naturally elevated levels of histamine, leading to more pronounced reactions.

Self-motivated Àڱ⵿±âºÎ¿©: A person who is undermethylated may be highly self-motivated in both school and work functions. They may not need any outside inspiration or encouragement to complete their work, they are fuelled internally by themselves.

Social isolation »çȸÀû °í¸³: Some individuals with undermethylation may isolate themselves from others and prefer to be left alone, especially during the completion of work.

Strong willed °­ÇÑ ÀÇÁö: Another characteristic that is found among those who are undermethylated is that of a strong will.

Undermethylation and Serotonin: Researchers speculate that undermethylation is associated with abnormally low levels of serotonin in the brain. While the mainstream media has lead most people to believe that low serotonin is always bad, clearly not all outcomes are poor. However, the fact that undermethylators tend to have low serotonin, it can make some of these individuals more prone to developing depression. It is estimated that 15% to 20% of people dealing with undermethylation tend to find it problematic; likely as a result of serotonergic deficits.

Undermethylation Treatment

Assuming you are suffering from undermethylation, there are numerous supplements you can consider for treatment. Generally treatment doesn’t yield drastic improvement overnight, and in some cases it can take 8 to 12 months before a person feels noticeably better. However, it is also important to realize that nutritional intervention can be highly effective and successful over the long-term.

Since undermethylation results in low levels of calcium, magnesium, methionine, and Vitamin B6 – it’s important to consider these for supplementation. Additionally it may be important to avoid folic acid as levels may be abnormally high throughout neurons. Correcting nutritional imbalances is considered an important step towards improving undermethylation symptoms.

Supplements for Undermethylation

Most people aren’t fans of taking pharmaceutical medications once they have pinpointed the problem of undermethylation. If you know for a fact that undermethylation is the problem, taking a targeted nutritional approach is your best bet. Work with a professional to determine what quantities of vitamins and/or “stack” you should be taking.

Choline

Calcium

Magnesium

Methionine

Omega-3 fatty acids

SAM-e

Vitamin B12

Vitamin C

Medication Outcomes

If you plan on taking a medication, some researchers have noted that outcomes among individuals with undermethylation are considered specific based on the type of drug utilized.

Antihistamines: Since those with undermethylation tend to have high levels of histamine, using an antihistamine may result in favorable effects.

Benzodiazepines: People taking benzodiazepines like Xanax tend to have unfavorable responses if they are suffering from undermethylation.

SSRIs: Those dealing with undermethylation tend to respond well to selective-serotonin reuptake inhibitors. These are antidepressant drugs that specifically increase the amount of extracellular serotonin. These are considered helpful among undermethylators because they have low levels of serotonin.

Vitamin B Complex: Those taking Vitamin B Complex may experience adverse effects. This is because the person already has high levels of folic acid (Vitamin B9) and the complex serves to further elevate it.


Does treating undermethylation or overmethylation cure mental illness?

Assuming you are a person who has a polymorphism of the MTHFR gene that is causing undermethylation or overmethylation, balancing the methylation process could drastically improve your mood or psychiatric symptoms.  While many people preach that treating “over” or “under” methylation with supplement stacks will “cure” you of your psychitric illness, it is important to realize that this isn’t often the case.

Addressing the methylation imbalances could significantly improve your symptoms and/or overall health.  However, it does NOT mean that you will be eventually cured of your severe anxiety or depression.  A considerable number of people do improve once they address their MTHFR mutations with nutritional-based therapy, but don’t isolate methylation as the sole cause of your mental illness.  Your condition may be a result of a collective number of other genetic and environmental factors.

Are you suffering from overmethylation or undermethylation?

It is important to avoid assuming that you are an overmethylator or undermethylator based on the symptoms listed above. While you may be one or the other, self-diagnosing based off of information you’ve read online may end up doing more harm than good. If you are serious about learning whether you truly have a methylation problem, get the MTHFR gene tested and have the results analyzed.


Determining whether you have an MTHFR mutation is the best way for you to get proof that supports your hypothesis of being an overmethylator or undermethylator. Using a treatment protocol for overmethylation or undermethylation when you have no actual methylation dysfunction may be more problematic than beneficial. If you have had your MTHFR gene tested and successfully treated your methylation dysfunction, feel free to share your experience in the comments section below.


[inc....histamin]...th2 polarity

flushing --rapid heart beat---profuse sweating

headache--migraine--insomnia

food allergies--seasonal allergies//urticaria--prickly heat--large swollen mosquito bites

//itchy---irritable//skin issues (eczema>>, psoriasis)

runny nose--bloody nose//asthma//exercise-induced asthma//chest tightness

car sick--seasickness--motion sickness in general//nausea--vomiting--stomach ache--loose stools

higher sex drive (not really a problem typically but good to know)--menstrual cramps


**OM<±¸¸®ÃàÀû »óÅÂ+/»ó´ëÀû ¾Æ¿¬°áÇÌ, ALPÀúÇÏ/±¸¸®ÃàÀû...¼¼·ê·ÎÇö󽺹Π»ó½Â[È÷½ºÅ¸¹Î Æı«...VCÆı«]/B3,9,12°áÇÌ(¸ÞÄ¥±â 󸮳­¸Á/µ¶¼ºÁõ°¡..homocys°ú´ÙÃàÀû(UM-OM°øÅë??)..µµÆĹÎ/NE/¼¼·ÎÅä´Ñ»ó½Â »óÅÂ..±¸°­±Ë¾ç/Ä¡¾Æ¼Õ»ó Áõ°¡...)----th1 polarity//±³Á¤> B3912C, ¾ÆÀ¯¸£Á¨¿ÃÇØÇÇDMAE(NEÀ¸·ÎºÎÅÍ °æÇÕÀûÀ¸·Î ¸ÞÄ¥±â Å»Ãë-->Epi»ý¼º °¨¼Ò->¾Æµå·¹³ëÅ©·Ò »ý¼ºÂ÷´Ü, Ach»ó½ÂÀ¯µµ¸ñÀû)>

**UM<±¸¸®Á¤»ó ¶Ç´Â °áÇÌ »óÅÂ+,¾Æ¿¬?...È÷½ºÅ¸¹Î»ó½Â/MgB6°áÇÌ-SGOT, SGPT, GGT, MCVÀúÇÏ --th2 polarity//º¹ÇÕºñŸ¹ÎÁ¦ ±Ý±â...¸ÞÄ¥±â °ø±Þ¸ñÀû/SAMe-MgB6 == HMÃàÀûÇü>

**ÆÄÀ̷Ѹ®¾Æ : B6-¾Æ¿¬°áÇÌ


http://www.beyondmthfr.com/the-gut-origin-of-methylation-problems/


[[Th1-Th2, balance ȸº¹]]

**Th1¿ì¼¼ÀÎ °æ¿ì : ¾ÆÀ¯¸£Á¨/¾×Æ®¿£, (¶Ç´Â Ä«ÆäÀÎ, ³ìÂ÷, ¶óÀÌÄÚÆæ, ·¹½ºº£¶óÆ®·Ñ, ÇÇÅ©³ë°Ô³î, Ä¿Å¥¹Î, Á¦´Ï½ºÅ×ÀÎ, Äõ¼¼Æ¾) -GSE

**Th2¿ì¼¼((»ó½ÂµÈ È÷½ºÅ¸¹Î °¨¼Ò ¸ñÀû..¾ÆÀ¯¸£Á¨/¾×Æ®¿£µµ »ç¿ë°¡´É??)) -È«»ï/°¨ÃÊ/Ȳ±â/Ÿ³ª¹Î/Æ÷µµ¾¾ÃßÃâ¹°/¾Ë·Î¿¡/¸¶ÀÌ´ÙÄÉ -Ÿ³ª¹Î-.. Allegra/AM..benadrylORprimalan/PM....Ä¿Å¥¹Î-Äõ¼¼Æ¾

**Th1-Th2 ¹ë·±½º ȸº¹ : GSE/pine bark. tribulus, rooibos

**Th1,2Áõ°¡·Î ÀÎÇÑ ¿°Áõ¹®Á¦ ¹ß»ý½Ã : bilberry(¾ÈÅä½Ã¾È), EGCG/silymarin/curcumin(¾ÆÀ¯¸£Á¨/¾×Æ®¿£), Quercetine, resveratrol, VD-W3FA-Ginko(Ÿ³ª¹Î)


===============


'¸ð¹ß Á¶Á÷ ³» ¾Æ¿¬ ¹× ±¸¸® ³óµµ¿Í ´ë»çÁõÈıº ÁöÇ¥¿ÍÀÇ »ó°ü°ü°è(¾ÆÁÖ´ëÇпø, 2008)'¶ó´Â ³í¹®¿¡ µû¸£¸é Ç÷û ±¸¸® ³óµµ¿Í ¾Æ¿¬/±¸¸® ºñÀ²ÀÌ ´ë»çÁõÈıºÀÇ ¹ßº´À²°ú ¿¬°üÀÌ ÀÖ´Ù°í º¸°íÇß½À´Ï´Ù. 

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1) Àν¶¸°ÀÇ ºÐºñ¿Í È°¼ºÀ» ÃËÁø//2) Àν¶¸° ½ÅÈ£Àü´Þ °úÁ¤¿¡ Á÷Á¢ Âü¿©//3) °©»ó¼± È£¸£¸óÀÇ È°¼ºÈ­¿¡ ±â¿©ÇÏ¿© ´çÀÌ Áö¹æÀ¸·Î ÇÕ¼ºµÇ´Â °ÍÀ» ÁÙÀÓ

¶ÇÇÑ Ç÷û ±¸¸®°¡ ³ôÀ¸¸é ºñ¸¸ÀÌ ¸¹À¸¸ç ±¸¸® ¼öÁØÀÌ °¡Àå ³·Àº ±º(Cu:0.8~1.5mg%)¿¡¼­´Â Ç÷¾Ð°ú Ç÷´çÀÌ ³·°í ¸ð¹ß ³» ±¸¸® ¼öÁØÀÌ ³ôÀº ±º¿¡¼­´Â ´ë»çÁõÈıºÀÇ À¯º´·ü Áõ°¡ÇÔÀ» º¸ÀÔ´Ï´Ù.

°Ô´Ù°¡ ¾Æ¿¬/±¸¸® ºñÀ²(Á¤»ó ¼ºÀÎ : Zn/Cu = 9.4Á¤µµ¶ó°í º½)Àº üÁú·® Áö¼ö ¹× º¹ºÎ µÑ·¹¿Í À¯ÀÇÇÑ À½ÀÇ »ó°ü°ü°è¸¦ °¡Áö´Âµ¥ ¸ð¹ß ³» ¾Æ¿¬/±¸¸® ¼öÁØÀÌ °¡Àå ³·Àº ±º(Zn/Cu≤3.33)¿¡¼­´Â Ç÷¾Ð »ó½Â, Àν¶¸° ÀúÇ×¼º°ú ´ë»çÁõÈıº ¹ß»ý À§Çèµµ°¡ 4¹è °¡·® Áõ°¡ÇÏ°í ÇãÇ÷¼º ½ÉÁúȯÀÌ ÃÊ·¡ÇÏ¸ç ¸ð¹ß ³» ¾Æ¿¬/±¸¸® ¼öÁØÀÌ °¡Àå ³ôÀº ±º(Zn/Cu≥10.01)¿¡¼­´Â Ç÷´çÀÌ ³·°í ´ë»çÁõÈıºÀÇ À¯º´·ü ¶ÇÇÑ À¯ÀÇÇÏ°Ô °¨¼ÒÇÔÀ» º¸ÀÔ´Ï´Ù.

¸ð¹ß Áß ¹Ì³×¶ö ÇÔ·®°ú Ç÷Áß ¹Ì³×¶ö ÇÔ·®À» ºñ±³ÇÑ ¿¬±¸¿¡¼­ ¸ð¹ß¿¡¼­ 10~10,000¹è¿¡ À̸£´Â ÇÔ·®ÀÇ Â÷ÀÌ°¡ Á¸ÀçÇÏÁö¸¸ ¸ð¹ß ¹Ì³×¶ö °Ë»ç´Â Àå±â°£¿¡ °ÉÃÄ ´©ÀûµÈ º¯È­¸¦ È®ÀÎÇϱâ À§ÇÑ À¯¿ëÇÑ ¼ö´ÜÀ¸·Î ¾Ë·ÁÁý´Ï´Ù. ºñ·Ï ¾Æ¿¬°ú ±¸¸®ÀÇ Á¤»óÄ¡¿¡ ´ëÇÑ ±¸Ã¼Àû ±âÁØÀÌ ¾ÆÁ÷ Á¤ÇØÁöÁö´Â ¾Ê¾ÒÁö¸¸ ¾Æ¿¬°ú ±¸¸® Áß ¾î´À ÇϳªÀÇ °úÀ×Àº ¼­·ÎÀÇ °áÇÌÀ» À¯µµÇϹǷÎ(±æÇ×ÀÛ¿ëÀ» ÅëÇÑ Ç×»ó¼º À¯Áö) Á¤±âÀûÀÎ ¸ð¹ß °Ë»ç¸¦ ÅëÇؼ­ ¾Æ¿¬°ú ±¸¸®ÀÇ ÀûÁ¤ºñÀ²À» ½Ä»ýÈ°·Î À¯ÁöÇÏ¿© ´ë»ç¼ºÁúȯÀ» ¿¹¹æÇϴµ¥ ÀÌ¿ë°¡´ÉÇϸ®¶ó »ý°¢Çغ¾´Ï´Ù.

Âü°í·Î ´ë»çÁõÈıºÀº NCEP-ATP IIIÀÇ ¾Æ½Ã¾Æ-ÅÂÆò¾ç Áø´Ü±âÁØ¿¡ µû¸£¸é ´ÙÀ½°ú °°½À´Ï´Ù.

1) º¹ºÎºñ¸¸ : Ç㸮µÑ·¹ ³²ÀÚ 90cm ÀÌ»ó, ¿©ÀÚ 80cm ÀÌ»ó

2) °íÇ÷¾Ð : 130/85mmHg ÀÌ»ó ¶Ç´Â °íÇ÷¾Ð¾àÀ» º¹¿ëÁßÀÎ °æ¿ì

3) °íÁß¼ºÁö¹æÇ÷Áõ : 150mmHg ÀÌ»ó ¶Ç´Â ÁöÁú °³¼±Á¦¸¦ º¹¿ëÁßÀÎ °æ¿ì

4) ÀúHDL-ÄÝ·¹½ºÅ×·ÑÇ÷Áõ : ³²ÀÚ 40mmHg, ¿©ÀÚ 50mmHg 

5) °íÇ÷´ç : °øº¹Ç÷´ç 110mmHg ÀÌ»ó ¶Ç´Â ´ç´¢¾àÀ» º¹¿ëÁßÀÎ °æ¿ì

-----------------------
**HMT»ó Zn/CuºñÀ²ÆÇ´Ü...>16(±¸¸®°áÇÌ, ±Ø½É)...8-16(±¸¸® °áÇÌ, °æ¹Ì)...4-8(±¸¸®µ¶¼º, °æ¹Ì)..2-4(±¸¸®µ¶¼º, ±Ø½É)
==¾Æ¿¬ Åõ¿©½Ã 15mg´ç ±¸¸®1mgÀ» Àû¾îµµ 4½Ã°£ °£°ÝÀ» µÎ°í Åõ¿©ÇØ¾ß ÇÔ....
==±¸¸®ºÎÁ·½Ã´Â öºÐÈí¼ö°¡ ¹æÇØ¹Þ°Ô µÊ [:: À§»ê»ý»ê(B1),ºñŸ¹ÎCµµ öºÐÈí¼ö¿¡ Áß¿ä], ...µû¶ó¼­ Ç÷û°Ë»ç»ó ALPÀúÇÏ, ºñŸ¹ÎD, ÈѸ®Æ¾, LDH °¨¼Ò½Ã¿¡´Â ¸ÕÀú ¹Ýµå½Ã ºÎÁ·ÇÑ ¿ä¼Òµé(ºñŸ¹ÎD-ÈѸ®Æ¾-B1)À» ºñ°æ±¸·Î ä¿ö ÁØ ÈÄ¿¡ ¾Æ¿¬°ú ÇÔ²² ºÎ°¡ÀûÀ¸·Î ±¸¸®¸¦ Åõ¿©ÇÏ´Â °ÍÀ» °í·Á..
------------------------
@°ú¸ÞÆ¿È­ÀÇ °æ¿ì °æÇèÇÏ´Â ¾Ë·¹¸£±âÆÐÅÏÀº ´ë°³ ´ë°³ À½½Ä¾Ë·¹¸£±â³ª È­Çй°Áú¹Î°¨¼ºÀ¸·Î ³ªÅ¸³² = ***À½½Ä¾Ë·¹¸£±â(Ưº°ÇÑ À½½Ä¿¡ ´ëÇÑ µÎµå·¯±â, --³ëÃâµÈÁö ´ë°³ ¼öºÐ~¼ö½Ã°£¾È¿¡ ±Þ°ÝÇÑ ÀÌ»ó¹ÝÀÀÀÌ ¹ß»ý...´ëÇ¥ÀûÀÎ °ÍÀÌ À¯´ç/±Û·çÅÙ/MSG/ÀÌȲ»ê¿°(¿ÍÀÎ)ºÒ³»ÀμºÀÓ... [À§Àå°ü¹ÝÀÀ]±¸°­¼Ò¾çÁõ/±¸¿ª-±¸Åä/¼³»ç/º¹Åë,[ÇǺιÝÀÀ]µÎµå·¯±â/½ÀÁø ¹ß»ý, [È£Èí±â¹ÝÀÀ]ÈĵκÎÁ¾/õ½Ä ¹ßÀÛ  = ***È­Çй°Áú¹Î°¨¼º/´Ù¹ß¼º È­Çйΰ¨Áõ(Multiple chemical sensitivity) : ....ÁַΠƯº°ÇÑ ³¿»õµé ƯÈ÷, Çâ¼ö-³ó¾à-Çöó½ºÆ½-ÇÕ¼ºÁ÷¹°·ù-¼®À¯Á¤Á¦Á¦Ç°-½ºÇÁ·¹ÀÌÇü ÆäÀÎÆ®/¿°»ö¾à-¿¬±â µî¿¡ ´ëÇØ ÁýÁßÀå¾Ö-ÇÇ·Î-µÎÅë-±¸¿ª-¾îÁö·³ µî °©ÀÛ½º·± ³ú¾Ë·¹¸£±âÇö»ó °æÇè.  ¼ºÀå±â ¾î¸°À̵éÀÇ °æ¿ì, °è¶õ-¿ìÀ¯-¶¥Äá/Äá·ù......¼ºÀεéÀÇ °æ¿ì,  ¶¥Äá/¿ù³Ó, Á¶°³·ù- »õ¿ì/°©°¢·ù......µÅÁöÇ®/ÀÚÀÛ³ª¹«È­ºÐ/¸Þ·Ð/º¹¼þ¾Æ/»ç°ú²®Áú
------------------------
@@Hair Analysis and the Zinc/Copper Ratio...Posted by Eileen Durfee on 7th Apr 2017
The Zinc/Copper (Zn/Cu) ratio is another important body mineral ratio that can be discovered through a hair analysis test. An imbalance between zinc and copper levels in the human body leaves a person more susceptible to infections and other unwanted health conditions including ear infections, skin rashes, and dandruff. Dr. Paul C. Eck, an expert in hair tissue mineral analysis, interprets the high and low ranges for Zn/Cu ratios on hair analysis test as indicative of potential internal issues that need to be corrected. 
Hair analysis test report zinc to copper ratio
Zinc/Copper Ratios and Indications on Hair Analysis Test Reports:
A high zinc to copper ratio, above 16, indicates severe copper deficiency or bio-unavailability
A ratio between 8-16 indicates copper deficiency or unavailability
A ratio of 8-1 is IDEAL
Ratios between 4-8 generally indicate copper toxicity
Ratios between 2-4 often indicate severe copper toxicity
High ratios of copper are found in the majority of vegetarians or vegans undergoing HTMA. Copper is balanced by zinc, and the best dietary source of zinc is red meat, which is why vegetarians and vegans are often low in zinc and high in copper. 
Zinc levels can also be lower in the body because zinc is not prevalent or present in soil, refined sugar, white rice, and white flour. 
Eating foods that contain high amounts of zinc helps to balance copper levels; however, consuming too much zinc during the copper elimination process can cause the body to replace copper in the liver. This results in copper being forced into the blood stream, which causes more aggravated copper elimination symptoms.
Symptoms that may occur due to excess copper and a zinc deficiency include:
Skin problems
Emotional instability
PMS
Reproductive problems
Prostatitis
Menstrual problems
Depression
Fatigue
Zinc and copper work closely together as part of the immune response. Zinc is highly anti-inflammatory and critical for proper immune response. Too much copper interferes with zinc metabolism and can accumulate when there is a zinc deficiency. In contrast, too much zinc tends to lower copper at an excessive rate which affects the estrogen level.
An elevated level of zinc, above 15 mg %, on a hair analysis is normally due to the presence of a copper. A level of zinc over 20 mg % can indicate hidden copper. This is why the ratio of these two minerals is so much more helpful than their individual levels. Get your hair analysis test today to learn about your body’s mineral ratios and get on your way to better health!
Related Posts:
The Calcium/Magnesium Ratio and Hair Analysis
Tackle Copper Toxicity with Hair Analysis
----------------------
**[MAST CELL ACTIVATION SYNDROME]
---ASD(Jasperger SD) ¿øÀαâÀü : ³úÀÇ ¿°Áõ(IL-6, TNF»ó½Â) + BBB¼Õ»ó by Mast cell activation Sx ((MCS)) -->hives(ƯÈ÷ »ýÈÄ ¼ö°³¿ù³»¿¡ Àü½Å¿¡ ¹ß»ý, ±×ÈÄ 40-50´ë¿¡ Àç¹ß...»ý¸íÀ§Çù°¡´É...ILÂ÷´ÜÁ¦¿Í Ç×È÷½ºÅ¸¹ÎÁ¦ º¹¿ëÀÌ ÇÊ¿ä) CFS(¸¸¼ºÇÇ·Î) FM(¼¶À¯±ÙÅë) interst.cystitis°£Áú¼º¹æ±¤¿° BAõ½Ä : induced by environmental factor + prenatal maternal stress(³ªÁß¿£ Àϱ¤ÀÌµç ±× ¹«¾ùÀÌµç ¸ðµç ÇüÅÂÀÇ ½ºÆ®·¹½º°¡ Æ®¸®°Å·Î ÀÛ¿ëÇÏ°Ô µÊ)....±×¿Ü¿¡ HgÃàÀû, °¨¿°Áõ(virus. Áø±Õ, bacteria)µµ À¯¹ß¿ä¼Ò·Î¼­ Áß¿ä  ===>(%CRHÀÇ Å¸°ÙÀº Àü½Å¿¡ ÀÖ´Â MastCell!!/BrainMastCellÀÇ Ç¥¸é¿¡ ÀÖ´Â CRH¼ö¿ëü ¹ßÇö½Ã VEGF°¡ À¯¸®µÊ = BBB°¡ ¿­¸®°Ô µÊ[BBBȸº¹Àº ¸á¶óÅä´ÑÀÌ ÁÖÈ¿!!]...¾ð¾î°ü·ÃBroca area¿Í °¨Á¤°ü·Ã Diencephalon/Hypothalamus¿¡ ¾Ç¿µÇⳢġ´Â °ÍÀÌ ASDÀÚÆó½ºÆåÆ®·³Àå¾ÖÀÓ)...³úÀÇ ºñ¹Ý¼¼Æ÷³»ÀÇ ¹ÌÅäÄܵ帮¾Æ°¡ TNF, IL-6µî¿¡ ÀÇÇØ ¼Õ»ó¹Þ°Ô µÇ¸é ºñ¹Ý¼¼Æ÷¿Ü·Î ¹èÃâµÇ°í ¹ÌÅäÄܵ帮¾ÆDNA¸¦ ¼¼±ÕÀ¸·Î ÀνÄÇÑ ¸é¿ª°è°¡ ¸é¿ª¿°Áõ¹ÝÀÀÀ» Ã˹ß/¹ÌÅäÄܵ帮¾Æ ±â´ÉÀÌ»ó ¾ß±â(¹«±â·Â)//ºñ¹Ý¼¼Æ÷-microglia»çÀÌÀÇ ¼¼Æ÷°£¼ÒÅëÀ» ÅëÇØ ÁõÆø......ASD(ADHD¿¡¼­µµ ¾ÆÅäÇǼº ÇǺο° µî ÇǺιßÁø°ú°Å·ÂÀÌ ÈçÇÔ!!...Áï, ÀÏÁ¾ÀÇ ºñ¹Ý¼¼Æ÷º´¸®±âÀü ÀÛµ¿??)¿¡¼­´Â ¶ò-¸Û, ÇÇ°ï. ÁýÁß·ÂÀå¾Ö=Brain fog¹ß»ý.....ÇǺιßÁø(½ÀÁø, ¾ÆÅäÇÇ)/ƯÁ¤À½½Ä¿¡ ´ëÇÑ ¾Ë·¹¸£±â ¶Ç´Â ºÒ³»Àμº/º¹Åë<¼ö¸éÀå¾Ö À¯¹ß>ÀÌ ºó¹ø....½ºÆ®·¹½º¸¦ ¸ø°ßµð´Â ½ºÆ®·¹½ººÒ³»Àμº, ´«Á¢ÃË/ÁÖÀÇ-ÁýÁß·Â °á¿©...¼ÒÅë·Â »ó½Ç...»ç±³¼º ÀúÇÏ µîÀÌ ASDÀÇ Æ¯Â¡==>MTOR Â÷´ÜÁ¦ÀÎ Luteolin(Ä«¸ð¸¶ÀϼººÐÀÇ Çö󺸳ëÀ̵å : ¿Ã¸®ºê¿ÀÀÏ¿¡ ´Ù·®ÇÔÀ¯..´Ù¸¥ Çö󺸳ëÀ̵嵵 µ¿ÀÏ È¿°ú..)+Äõ¼¼Æ¾(ÀÚ¸ù¿¡ ¸¹´Ù)ÀÌ ºñ¹Ý¼¼Æ÷È°¼º¾ïÁ¦Á¦·Î¼­ ¸Å¿ì µµ¿òµÊ/Brain fog°³¼±(ƯÈ÷ Ä«¸ð¸¶ÀÏ Æ¼) ..((ºñ¹Ý¼¼Æ÷¾ïÁ¦Á¦·Î ±âÁ¸¿¡ ¾Ë·ÁÁø Å©·Î¸ô¸°¼ÒµãÀº µ¿¹°¿¡¼­´Â Àß µèÁö¸¸ »ç¶÷¿¡°Ô¼­´Â º°·Î È¿°ú ¾ø´Âµí...))
--[ÀåÇص¶, ºÎÁ·¿ä¼Ò±³Á¤, ¼³ÅÁ/Á¤Á¦/ÀνºÅÏÆ®½ÄÇ°(±Û·çÅÙ/Ä«Á¦ÀÎ)±ÝÁö----
@@ADHD ::: (Doctor's Best)5-HTP, Enhanced with Vitamins B6 & C, 
--B3 (500mg Tid  ==>1000mg Tid) //--C (50mg==>1000mg qD) with or without B6//--5-HTP(tryptophan) 10mg==>100mg(at bed) (with or without DLPA) //W3FA + ºñŸ¹ÎD +¸ÞÆ¿Æú·¹ÀÌÆ®/¸ÞÆ¿Äڹ߶ó¹Î +°õÅÁ
@@ASD :: ¾çÆÄÁó(luteolin Quercetin) +¸á¶óÅä´Ñ/5-HTP(¼­¹æÇü) +À¯»ê±ÕÁ¦/±èÄ¡ +¸óÅ×·çÄ«½ºÆ®(ar10) +W3FA + ºñŸ¹ÎD +¸ÞÆ¿Æú·¹ÀÌÆ®/¸ÞÆ¿Äڹ߶ó¹Î +°õÅÁ
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