Á¦  ¸ñ :   dry eye, sea buckthorn

###Banishing Dry Eyes Naturally -By Dr. David Blyweiss on 08/20/2011

 

You¡¯ve seen the commercials—an attractive woman plagued by dry eyes, a condition that can affect a third of those over the age of 50. Her only hope A prescription for Restasis, a drug designed to make tears for her. The problem with this scenario is that this remedy doesn¡¯t work for everyone.

 

Of more concern, Restasis can cause a burning sensation, eye redness, discharge, watery eyes, eye pain, foreign body sensation, itching, stinging and blurred vision—all of the symptoms you are trying to relieve. Artificial tears aren¡¯t any better since they are just a quick—and temporary—fix for dryness.

 

Tears are essential to lubricate the eye and maintain healthy vision. They are made up of a combination of water, oils, mucus, antibodies and special proteins that help the eyes resist infection. These components are secreted by special glands located around the eye. Dry eye, technically known as keratoconjunctivitis sicca, occurs when there is an imbalance in this tear system—the eyes either don¡¯t make enough tears or the tears evaporate too quickly. Unfortunately, conventional medicine doesn¡¯t have a cure for this irritating problem. But a new study out of Finland offers a glimmer of hope in the form of a little-known nutrient called sea buckthorn.

 

Sea buckthorn is a shrub that grows in China, Russia and the Netherlands. Originally grown to prevent soil erosion, it¡¯s come to the forefront lately because of its rich nutritional profile. The plant¡¯s golden-orange fruit provides hefty amounts of vitamin C, vitamin E, lycopene, zeaxanthin, oils rich in essential fatty acids, and other healthful components that benefit eyesight. Now, this new study suggests that sea buckthorn can reduce the symptoms of dry eye, too.

 

The researchers recruited 86 people between the ages of 20 and 70 to participate in the double-blind, randomized, parallel trial. Each of the participants were randomly assigned to receive either two grams of sea buckthorn oil or a placebo oil every day for three months. People with both types of dry eye syndrome were included – people who can¡¯t make enough of their own tears, and people whose tears evaporate too quickly.

 

The results showed that all the participants experienced an increase in tear evaporation, but the people receiving the sea buckthorn supplement experience a significantly less evaporation. Furthermore, those who stuck with the regime and took at least 80 percent of their supplements experienced the greatest reduction. The people in the sea buckthorn group also had considerably less redness and burning.

 

The researchers conducting the study believe that the linolenic acid in the oil is responsible for reducing inflammation that contributes to dry eye syndrome. They also noted that sea buckthorn oil is a rich source of vitamins C and E, and that these antioxidants may protect the eye from oxidative damage.

 

Of course, the benefits of this nutrient-rich berry aren¡¯t confined to the eyes. Sea buckthorn has been reported to have a number of other health applications. Used topically, emerging research suggests that it can help ease eczema and other dry skin problems. It can also help guard against sun damage that can lead to prematurely-aged skin. Taken orally, sea buckthorn can protect against mouth dryness, gastric ulcers, urinary tract inflammations, inflammation of the cervix, genital ulcers and sinus inflammation. There is also some preliminary evidence that this novel supplement can ward off liver disease.

 

Whether you suffer from dry eye or not, adding sea buckthorn to your daily regime is something I highly recommend. While you can find it in capsule form, I like to take one to three ounces of sea buckthorn juice with breakfast every morning. It¡¯s a tasty and nutritious way to start the day and help ensure moist, healthy eyes

 

Related articles of interest:

Testosterone for Dry Eye Syndrome

Is Blindness In Your Future

How to Protect Your Health In The Computer Era

 

References:

Geetha S. Hepatoprotective effects of sea buckthorn (Hippophae rhamnoides L.) against carbon tetrachloride induced liver injury in rats. Journal of the Science of Food and Agriculture. 2008;88:1592-1597.

Gutzeit D. Nutritional assessment of processing effects on major and trace element content in sea buckthorn juice (Hippophaë rhamnoides L. ssp. rhamnoides). Journal of Food Science. 2008;73:H97-102.

Larmo PS. Oral Sea Buckthorn Oil Attenuates Tear Film Osmolarity and Symptoms in Individuals with Dry Eye. Journal of Nutrition. 16 June 2010. Published online ahead of print, doi: 10.3945/jn.109.118901


###¾¾¹÷½¼(sea Buckthorn)¿ÀÀÏ   http://blog.naver.com/skinus/60131704447
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###Testosterone for Dry Eye Syndrome --By Dr. Jeffrey Dach on 04/08/2010

 

     Mrs. B was 58 years came to see me because of dry itchy, red eyes. Her lids would sometimes swell because of the irritation. She had the typical menopausal symptomsof night sweats and hot flashes as well. 

 

     Over the years, Mrs B had been to numerous eye doctors who gave her various drops to lubricate the eye, antibiotic drops and steroid drops. She has been given instructions for cleaning and irrigating the eyes. The eye drops seem to help somewhat but the irritation always returns whenever she stops them. Lately, the condition is getting worse and nothing seems to help.

 

@Low Testosterone Level

A routine hormone panel showed that Mrs B had low hormone levels, and her testosterone level was especially low. I explained to Mrs B that her dry eye syndrome was caused by low testosterone levels, and testosterone would help.

 

@Cured With Testosterone, Surely You Must Be Joking, Doctor

     Six week later, after starting her testosterone as sublingual drops, Mrs B reported her eyes were much better. She also started a complete bioidentical hormone program.

     Mrs B's ophthalmologist, Dr H, was an old friend of mine and we would occasionally attend the same social functions. At one of these social functions, Dr H approached to say that a patient (no name) reported that I had cured her dry eyes with testosterone, and surely you must be joking, Doctor. His gesture and facial expression with his eyes rolling back were quite distinctive.

 

@Testosterone for Dry Eyes in the Opthalmology Medical Literature

     Apparently, Dr H is unaware of the supportive evidence in his own specialty medical journals. We will look at a few of these supportive articles that recommend testosterone for evaporative dry eye syndrome. About 5 million Americans have Dry Eye Syndrome caused by dysfunction of the lubricating glands, which are called the lacrimal and meibomian glands. The small glands at the upper outer eye are the lacrimal glands, and the meibomian glands are located in the eye lid at the upper and lower edges.

 

@Dr David A Sullivan and Dry Eye Research

     Much of the research on testosterone and dry eyes has been done by David A. Sullivan, at Schepens Eye Research Institute at Harvard Medical School.

 

@Dr Sullivan Research in Mouse Model Of Sjogren's

     Dr. Sullivan's early work in the 1990's involved Sjogrens syndrome, and the discovery that women with Sjögren's syndrome are androgen-deficient causing meibomian gland dysfunction, tear film instability, and the evaporative dry eye characteristic Sjogren's, which is an autoimmune disorder. Sullivan published a study in 1991 which showed that testosterone inhibited the progression of autoimmune disease in the lacrimal glands mice with Sjogren's. His mouse model of Sjogren's showed that the testosterone suppressed the magnitude of lymphocyte infiltration in the lacrimal gland 22- to 46-fold.

 

@Lacrimal and Meibomian Glands Regulated by Testosterone

     In a 1999 report, Sullivan suggested that androgens (testosterone) regulate both lacrimal and meibomian gland function, and suggest that eye drops containing testosterone may be safe and effective treatment for dry eyes in Sjögren's syndrome.

 

@Men on Testosterone Blockers Get Dry Eyes

     In 2000, Dr Sullivan reported that men taking testosterone blockers have dry eye syndrome. Men on testosterone blocker drug treatment for prostate cancer were found to had poor quality of tear fluid. This was demonstrated by analyzing the meibomian gland secretions. Their dry eye symptoms included light sensitivity, painful and blurry eyes. Sullivan said,"the use of anti-androgen pharmaceuticals was associated with significant changes in the relative amounts of lipids in meibomian gland secretions. Our findings indicate that chronic androgen deficiency is associated with meibomian gland dysfunction and dry eye."

     In 2001, Drs Worda and Nepp from Vienna Austria reported that topically administered androgen can restore the lipid phase of the tear film, and was useful in treatment of keratoconjunctivitis sicca, medical terms for Dry Eyes.

 

@Complete Insensitivity to Androgen and Dry Eyes

      Next, Dr Sullivan turned his attention to a genetic disorder called Complete Insensitivity to Androgen (CIAS). In this genetic disorder, the androgen receptor is nonfunctional, and subsequently, there is insensitivity to testosterone. Without a functioning receptor, the normal activity of testosterone is completely blocked.

     Dr Sullivan examined the tears (ie. Meibomian gland secretions), in women with CIAS and compared them to normal controls. The patients with CIAS had alteration in the lipid fractions of tear fluid, ( ie meibomian gland secretions). This study was published in a 2002 report in Arch Ophthalmology.

 

@Trans-Dermal Testostorone For Dry Eye Syndrome

In 2003, Dr Connor reported transdermal testosterone is safe and effective treatment for dry eye, with the post-menopausal females having the greatest relief of symptoms.

 

@Molecular Biology Mouse Studies of Gene Expression

     In 2005, Dr Schirra et al studied the molecular biology of testosterone, and gene expression in the meibomian gland of mice. Dr Schirra reported that testosterone regulates the expression of more than 1500 genes in the mouse meibomian gland which serves to stimulate lipid and fatty acid metabolism in the lubricating eye fluid.

 

@The Evidence is Overwhelming

     The sum total of the above evidence is overwhelming that testosterone playes a key role in production of oil, the lipid component for lubricating the eyes, and that testosterone deficiency is a treatable cause of dry eye syndrome. The treatment is testosterone, a bioidentical hormone

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