| ###The Hot New Way To Destroy Fat Cells -- By Cassandra Forsythe-Pribanic, PhD, RD
***fat burner : capsaicin 500mg + green tea extract(EGCG 300mg + caffeine) with tomatoe juice. before 20 min. workout starting
We’ve all seen them: those novelty condiment stores, usually in the Southwest part of the US, that carry every hot and spicy seasoning created. From Mad Dog Firey Sauce to Holy Jolika Hot Red Pepper Sauce, you just know your taste buds are going to cry in pain. Nevertheless, for some (insane) reason, you still add a drop or two to your food. It’s like riding a roller coaster; you experience an extreme, heart-pounding, thrill of hurdling your body through the air without actually causing any permanent harm (other than a near heart attack). With these hot red pepper sauces, you’ve created a feeling of danger within your senses that sends your heart racing and your sweat glands pouring. And, at the same time - if you didn’t know it already -you’ve adding one more arsenal to your fat loss battle. What could be better
@@@Hot Red Peppers: The Weight Loss Weapon of Choice
I know what you must be thinking: “Of course hot peppers can help me lose weight, when I put them in my food I can barely eat one bite! Not being able to eat food equals weight loss. Duh!”
Well, this may be true, but who wants to starve themselves to fit into their favorite pair of jeans And, what if I told you that you don’t even have to put hot peppers in your food for them help you lose a pant size
That’s right, much of the scientific research performed with red hot peppers is done in an encapsulated form, and is found to be more effective than when it’s placed in food. Yes, there are studies with capsaicin (the active ingredient in hot red pepper) added to food, but it comes with compliance limitations – people can’t eat it on a regular basis because it’s too hot. Also, it’s suggested that the effects of capsaicin accumulate over time to produce greater results. Research subjects who take extracts of this fiery fat burner in a capsule form show more benefits for energy expenditure and weight loss than those who take it in a meal (Yoshioka M et al, 2004).
But, this all comes within the context of a healthy eating pattern; you can’t binge and purge, or add hot red pepper capsules to a diet of coffee and donuts and expect it to make a difference. You also have to exercise. No dietary supplement will ever cause the weight to melt off you if you don’t put in some additional physical work. It doesn’t matter if it’s training for your local 5K run or if it’s kicking your own butt in bootcamp class, you still need to make an effort to lose unsightly body fat.
@@@What is Capsaicin
Capsaicin is the major heat-producing component in hot red peppers. These peppers come from plants belonging to the genus Capsicum, which include sweet bell peppers (red, yellow and green), and hot chili peppers (ancho, banana, habanero, jalepeno, etc). Obviously hot peppers contain more capsaicin than sweet bell peppers, and in fact, sweet bell peppers don’t contain any capsaicin at all due to a recessive gene that eliminates its production.
The amount of capsaicin, or spicy heat, delivered in a pepper is rated within a unit of measure called the Scoville scale. The number of Scoville Heat Units (SHU) in this scale tells you how much capsaicin is present. Below is a chart showing you Scoville ratings of different peppers with pure capsaicin (also spelled capsaician) having the highest ranking and bell peppers having the least.
Capsaicin is found within the fleshy parts of peppers that holds the seeds, mainly the pepper membranes. In fact, the seeds themselves do not produce any capsaicin, although the highest concentration of capsaicin can be found in the white pith around the seeds
@@@How Does Capsaicin Help You Get Rid of Body Fat
There are three main mechanisms by which capsaicin can help you fight the battle of the bulge:
1. Increases energy expenditure
2. Deters fat cell growth
3. Reduces food intake
@Enhanced Energy Output
Through activation of the sympathetic nervous system (SNS), capsaicin increases catecholamine secretion from the adrenal medulla, which stimulates beta-1-adrenergic receptors in the body (Diepvens K 2007). These receptors increase activity of muscular tissues responsible for increasing heart rate, contracting blood vessels and dilating airway passages – the “Flight or Fight” syndrome. All of these actions increase your total energy output and burns extra calories. And, in support, both human and animal studies have shown that the increased thermogenesis (calorie-burning) from capsaicin is abolished when beta-adrenergic blockers, such as propanolol, are administered.
Another route for amplified thermogenesis from capsaicin is both up- and down-regulation of uncoupling proteins (UCP) in the body (Faraut B et al, 2007, Masuda Y et al, 2003). The uncoupling proteins 1, 2 and 3 (UCP1, UCP2, and UCP3) are negative ion carrier-proteins located in the inner membrane of mitochondria (the power house of your cells). These proteins are greatly responsible for increased energy expenditure via cellular energy wastage (losing energy instead of storing it). Animal and cellular research has shown that various capsaicin dosages can stimulate these UCPs and cause enhanced calorie-burning.
In recognition of these cellular and animal studies, human studies with capsaicin have also shown improved energy output following hot red pepper intake. Japanese researchers showed that when 10 g of powdered hot pepper (containing capsaicin) was added to either a high fat or high carbohydrate mixed meal, diet-induced thermogenesis (energy expenditure from eating a meal) was significantly increased for up to 3 hours following the meal (Yoshioka M et al, 1998).
Other Japanese researchers showed 3 mg of hot red pepper increased energy expenditure in lean, healthy women by 10% for 30 minutes (Matsumoto T et al, 2000), while Lim et al, 1997 showed an energy expenditure increase of 25% in healthy lean young mean also for 30 minutes following 10 g of hot red pepper intake.
@Fat Cell Fighter
Capsaicin from hot red peppers has been shown to actually change how fat cells function. Instead of growing larger and larger like they usually do, capsaicin can help shrink fat cells by making them more metabolically active.
Recently reported in the 2010 Journal of Proteome Research (Joo JI et al, 2010), using a novel research tool called proteomic analysis, Korean scientists demonstrated that capsaicin changed the activity of proteins found within white adipose tissue (WAT) – aka, unsightly body fat – of rats and made these proteins act more like those found in brown adipose tissue (BAT). BAT is the type of fat tissue only found in infants and hibernating bears that produces and expends energy rather than stores it. These scientists suggest that capsaicin can remodel WAT into mitochondrial-rich cells, with their high capacity for fatty acid oxidation, and reduce our over-abundance of human obesity. Although this research was done in animals, it explains many of the fat-fighting effects attributed to hot pepper consumption.
Also reported in the Journal of Agricultural and Food Chemistry (Chin-Lin Hsu et al, 2007), Taiwanese researchers found that when capsaicin was applied to immature adipocytes (fat cells), it both inhibited adipogenesis (fat cell growth) and differentiation (change into mature fat cells). Thus, the cells did not increase in size or turn into full-grown fat cells.
Then, in humans, people given a supplement containing 0.4 mg capsaicin and 625 mg green tea extract for two weeks showed a drop in body fat compared to their starting values. The effects were more prominent in those with higher body fat levels, but were consistently decreased in each person (Tsi D et al, 2003).
@Reduced Food Consumption
Yes, adding hot red pepper extract to food could make you eat less because your tongue feels like it’s on fire, but in the research setting, human investigations have shown diminished food intake following hot pepper supplementation.
Researchers from the Netherlands took healthy men and women and gave them a supplement containing 0.9 g hot red pepper (0.25% capsaicin; 80, 000 Scoville heat units) with tomato juice 30 minutes before they consumed four daily meals. After taking the capsules, total energy intake and fat intake was significantly decreased, while satiety was significantly increased, in both men and women (Westerterp-Plantenga MS et al , 2005). Thus, even in the short term, capsaicin can help decrease the amount of food you’d normally eat.
In a similar study, researchers in Quebec (Yoshioka M et al, 2004) also gave healthy, fit, men and women capsules containing 0.9 g of hot red pepper (0.3% capsaicin/ 55 000 Scoville Heat Units) 10 minutes before they were presented with a buffet of food that they were told to eat until they were full. This was compared to adding hot red pepper extract to a soup before hitting the buffet. All subjects were required to finish eating within 30 minutes. After analysis, the researchers found that food intake was decreased by an average of 8.5% compared to several different placebo and lower dose conditions – mostly from a significant decrease in fat intake (<13.3%).
These scientists found that that mechanism by which capsaicin reduced food intake occurred after it had passed through the mouth (thus, your tongue doesn’t have to suffer), and involves activation of the SNS: heart rate variability was significantly increased with the capsules compared to no capsules and to a soup that the subjects considered to be too spicy due to the addition of hot red pepper (i.e., an intolerably spicy meal actually desensitizes neurons and has no effect on food intake). Therefore, to get maximal benefits from capsaicin in your quest to eat less food and control your body weight, you don’t have to experience fiery feelings within your mouth, or ruin a good, healthy meal.
One of the mechanisms for improved satiety with capsaicin intake is changes in gut hormones responsible for stimulating hunger. The same researchers from the Netherlands (Smeets AJ & Westerterp-Plantenga MS, 2009) found that a meal containing capsaicin increased the hormone GLP-1,which stimulates satiety, and lowered ghrelin, which also tells the brain you’re full.
@@@Capsaicin: Your Fat Loss Tool of Choice
As you’ve now learned by several different scientific sources, capsaicin can assist you in fighting body fat and changing your body for the better. By increasing energy expenditure, interfering with fat cell growth and helping you eat less, the active component of hot red peppers, capsaicin, can help you shed unwanted pounds and reach your body composition goals. And the best part You don’t have to overheat a great meal to get the effects! Instead, you can take this pungent powerhouse in capsule form to get all the great body-beautifying benefits. But, if you still enjoy the taste of Franks Red Hot Sauce or Death Valley Drops, go ahead and indulge – if anything, it’ll help you eat even less, but will still let you experience the thrill of near-death encounters.
The Most Important Discovery For Weight Loss In The Last 50 Years >>
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@L-Tyrosine: Two servings of METABOLISM supplies 175% of the dose of this naturally-occurring amino acid found to reduce food intake in healthy subjects1. In the same study, tyrosine caused subjects to burn a greater proportion of calories from fat.*
@DL-Methionine, Inositol and Choline Bitartrate; Vitamins B-6, B-12: This team of important nutrients was added to METABOLISM to support the movement of fat in the body and its efficient conversion into usable energy (“calories burned”).*
@Green tea extract: The green tea extract found in each serving of METABOLISM is sourced from China (who knows green tea better). It contains more than 112% of the dose of epigallocatechin gallate (EGCG) ingested by the subjects in the study that reported a 3.5% increase in 24-hour calorie-burning rate2
@Cinnamon: R&D scientists chose to use a concentrated extract of cinnamon bark in a dose equivalent to 1 gram of whole cinnamon. This is within the range of doses used in studies investigating cinnamon’s beneficial effects on insulin sensitivity and blood glucose regulation, both of which may factor into the weight loss equation.*
@Caffeine: We selected a dose of caffeine that’s been proven to increase calorie-burning rate in healthy subjects3
@Capsaicin: Research subjects who take extracts of this natural fat burner in a capsule form show more benefits for energy expenditure and weight loss than those who take it in a meal (Yoshioka M et al, 2004).
@@@ Resources:
Joo JI et al. Proteomic analysis for antiobesity potential of capsaicin on white adipose tissue in rats fed with a high fat diet. J Proteome Res. 2010 Jun 4;9(6):2977-87.
Lim K et al. Dietary red pepper ingestion increases carbohydrate oxidation at rest and during exercise in runners. Med Sci Sports Exerc. 1997 Mar;29(3):355-61.
Yoshioka M et al. Combined effects of red pepper and caffeine consumption on 24 h energy balance in subjects given free access to foods. Br J Nutr. 2001 Feb;85(2):203-11.
Yoshioka M et al. Maximum tolerable dose of red pepper decreases fat intake independently of spicy sensation in the mouth. British Journal of Nutrition , Volume 91 , Issue 06 , Jun 2004 , pp 991-995
Tsi D et al. Clinical study on the combined effect of capsaicin, green tea extract and essence of chicken on body fat content in human subjects. J Nutr Sci Vitaminol (Tokyo) 49: 437–441, 2003
Faraut B et al. Downregulation of uncoupling protein-3 in vivo is linked to changes in muscle mitochondrial energy metabolism as a result of capsiate administration. Am J Physiol Endocrinol Metab 2007; 292: E1474–E1482.
Snitker S et al. Effects of novel capsinoid treatment on fatness and energy metabolism in humans: possible pharmacogenetic implications. Am J Clin Nutr 2009; 89: 45–50.
Masuda Y et al. Upregulation of uncoupling proteins by oral administration of capsiate, a nonpungent capsaicin analog. J Appl Physiol 2003; 95: 2408–2415.
Lejeune MP, Kovacs EM, Westerterp-Plantenga MS. Effect of capsaicin on substrate oxidation and weight maintenance after modest body-weight loss in human subjects. Br J Nutr 2003; 90: 651–659.
Westerterp-Plantenga MS, Smeets A, Lejeune MP. Sensory and gastrointestinal satiety effects of capsaicin on food intake. Int J Obes (2005) 2005; 29: 682–688.
Ohnuki et al. CH-19 sweet, a non-pungent cultivar of red pepper, increased body temperature and oxygen consumption in humans. Biosci Biotechnol Biochem 2001; 65: 2033–2036.
Smeets AJ, Westerterp-Plantenga MS. The acute effects of a lunch containing capsaicin on energy and substrate utilisation, hormones, and satiety. Eur J Nutr 2009; 48: 229–234.
Yoshioka, M et al. Effects of red pepper on appetite and energy intake. Br. J. Nutr. 1999, 82, 115−123.
Dulloo AG. Spicing fat for combustion. Br J Nutr. 1998 Dec;80(6):493-4.
Yoshioka M et al. Effects of red pepper added to high-fat and high-carbohydrate meals on energy metabolism and substrate utilization in Japanese women. British Journal of Nutrition, Volume 80, Issue 06, December 1998, pp 503-510
Chin-Lin Hsu and Gow-Chin Yen, J. Effects of Capsaicin on Induction of Apoptosis and Inhibition of Adipogenesis in 3T3-L1 Cells. Agric. Food Chem., 2007, 55 (5), pp 1730–1736
Diepvens K et al. Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea. Am J Physiol Regul Integr Comp Physiol 292: R77-R85, 2007
Matsumoto T et al. Effects of capsaicin-containing yellow curry sauce on sympathetic nervous system activity and diet-induced thermogenesis in lean and obese young women. J Nutr Sci Vitaminol (Tokyo). 2000 Dec;46(6):309-15
###"Release" Your Fat Cells(Lipolysis) ---By Kevin DiDonato MS, CSCS, CES
Fat cells are amazing and they can be your best friend!
That's right - you should embrace your fat cells.
As a review, you have learned what fat cells are (endocrine organ), and what a sick fat cell is (dysfunctional fat cell), but we also found out how the body splits and burns fat cells (lipolysis) obliterating them forever.
But there is more to it! Let's see how an adipocyte releases a fat cell to be processed in the first place.
If you want to increase metabolism, your metabolism (a KEY to losing weight and keeping it off), two things, and just two things, MUST happen.
First, the stimulation of the cell releases hormones. These hormones cause fat cells to be released, enabling them to be split and sent to the bloodstream.
And second, once released into the blood, fatty acids are shuttled to muscles and other cells to be used for energy.
We also know epinephrine and norepinephrine, once produced, bind to the surface of cells. But what do they bind to Answer: β-receptor cells.
@@ β-Adrenergic Receptor Cells
The stimulation of lipolysis in the adipose tissue requires communication from a lot of different parties.
We mentioned in previous articles, lipolysis, or fat breakdown, occurs with the help of different physiological processes. First, the body produces epinephrine and norepinephrine, causing a sympathetic response by the body. This causes blood from non-essential organs to be re-routed to the skeletal muscle. This stimulates the release of sugar and fatty acids, which enter the blood stream and head toward the skeletal muscle. You also see increased blood pressure and heart rate from the activation of the fight or flight system. This response requires massive amounts of energy, which are released from skeletal muscle, liver, and fat cells.
Epinephrine binds to the surface of the cell, stimulating β3 receptor cells. This produces adenylate cyclase, which then increases intracellular levels of cAMP which increases PKA levels in the cell. The binding of epinephrine and norepinephrine create a cascade of events starting lipolysis.
β-cells are not only found in adipose tissue, but are also found in the urinary bladder, gallbladder, and brown adipose tissue. β cells stimulate vasodilation allowing blood and nutrients to reach areas of the body quickly. The main responsibility of β cells is to stimulate lipolysis and thermogenesis in both types of human fat cells.
@@ Brown Adipose Tissue and Thermogenesis
As babies, we have high levels of brown adipose tissue. This tissue's main responsibility is to maintain temperature of muscles through shivering and non-shivering thermogenesis. This type of tissue is unique from adipose tissue due to its makeup and some other special things it can do.
Brown adipose tissue also has β-adrenergic cells in its makeup. They also possess higher levels of mitochondria, which help to trap and burn fatty acids for energy. I mentioned before how brown fat has some unique features! This tissue has great capacity for utilizing fatty acids, and it lacks storage capacity for fatty acids! Less fat storage=more fat used=more fat lost!
Brown fat also maintains thermogenesis, keeping the body warm. Normal cell processes use an energy source called ATP for most cellular functions. However, brown fat does not require ATP for its fat burning. When the fatty acid move into the mitochondria, there is increased heat and oxidation, which increases thermogenesis and burns more calories!
@@ Citrus Aurantium and Stimulation of β-cells
An extract of citrus fruit, citrus aurantium, has been used widely as a way to aid in weight loss. In the 1990s, ephedra was a potent stimulate for fat burning. Due to adverse reactions, ephedra was pulled from the shelves, only to be re-released. During the ephedra-free time, people were looking for an alternative to speed up metabolism and burn more fat. People then turned to citrus aurantium, commonly referred to as bitter orange.
Citrus aurantium is a natural beta adrenergic agonist, which means it stimulates β-cells to do its job. This powerful nutrient has many adrenergic amines which can increase metabolism, stimulate lipolysis, and allow more amino acid to be used by skeletal muscles.
Bitter orange and blood pressure have been one area of concern. One side effect of ephedra was an increase in blood pressure and heart rate. A component in bitter orange, synephrine, is closely matched to ephedra in chemical structure. People feared a similar increase in blood pressure and heart rate. Therefore, supplements were running into the same problems which faced ephedra.
However, to put your mind at ease, research done by Seifert et al. determined bitter orange does not raise blood pressure or heart rate, but instead, did increase resting metabolic rate and fat oxidation (breakdown) in certain populations.
Recent research completed in April, found similar conclusions as Seifert! Research done by Stohs et al. determined bitter orange containing p-synephrine (Advantra Z), appears to be safe with no adverse reactions linked to its use. They also mentioned millions of people consume citrus-related products which contain synephrine (Advantra Z) with no reported adverse effects to date.
@@ So how does it work
When β-adrenergic agonist is introduced, it stimulates cells to begin the process of lipolysis. Research by Fisher et al. determined prolonged exposure to β-agonists increased fat oxidation and adipocyte activation, but it also increased energy expenditure through brown adipose tissue. The theory behind the brown adipose tissue was the increased activation of a specialized molecule found in the mitochondria. Increased activation of uncoupling protein 1, uncouples oxidative phosphorylation, leading to an increase in energy expenditure. They also determined acute exposure to β-agonists results in increase lipolysis and elevated metabolic rate.
@@ To sum it up...
β-adrenergic cells are activated by hormones, which can be secreted by adipose tissue and adrenal glands, starting the process of lipolysis. β-cells are found in adipose tissue and brown adipose tissue in both adults and infants. Both tissues, when stimulated, begin the process of breaking down fatty acids for increased metabolic rate and lipolysis (adipose tissue) and increase energy expenditure, which increases thermogenesis (brown fat) in the body.
Citrus aurantium (Advantra Z) can increase metabolic rate, thermogenesis in brown fat, and adds appetite suppression, leading to feeling full and satisfied after a meal. Citrus aurantium is safe and effective for losing weight and increases metabolism with no reported increases in blood pressure and heart rate.
@@@ Five Of The Best Foods For Fat Loss--By Kevin DiDonato MS, CSCS, CES
Everyone wants to eat right and/or lose weight. But not everyone knows what the best foods for fighting belly fat are. Protein, fat, and carbohydrates (yes I said carbohydrates) will feed your metabolism-boosting lean mass helping you destroy belly fat forever! So what are the best foods for blasting away belly fat
Here is a list of my top five foods for weight loss:
#5 Eggs
Words cannot describe the fat fighting power of eggs. One egg has high-quality protein, and plenty of essential nutrients like choline all in 70 calories.
Pair with organic greens, a piece of whole wheat toast, and an apple or pear and you are well on your way to providing your body with fat fighting nutrients, including plenty of fiber to keep you feeling fuller for longer throughout the day.
#4 Apples or pears with skin
Apples and pears are another great way to add extra fiber to your diet. One large apple gives you 5 grams while 1 large pear gives you 7 grams of fat-fighting fiber. Fiber is perfect for curbing your appetite, which makes you eat less at meals or when snacking. Not only do pears and apples provide plenty of fiber, but they are fat free and cholesterol free. An apple gives 65 calories and a pear about 100 calories, making it a perfect healthy snack or a side dish at breakfast, lunch, or dinner.
Pair together with low-fat cheese, yogurt, or all natural peanut butter to provide essential amino acids and making it a wholesome and nutritious snack
#3 Greek Yogurt
So do Greeks know something we don’t This amazing food is a staple in Greek and Mediterranean cultures and is frequently given to a bride and groom on their wedding night for vitality, energy, and strength. Why is Greek yogurt so good for you Your typical yogurt is double filtered but Greek yogurt is triple filtered, resulting in a very creamy texture. Greek yogurt is higher in protein and lower in carbs than most commercial yogurts. This is a perfect treat for Diabetics and people who are low-carb crazy!
Pair this together with nuts and a touch of honey for a sweet and savory treat packed with fat burning protein, low carbohydrates, and a healthy dose of fiber.
#2 Sprouted Whole Grain (SWG) Breads
Considered the “flourless” bread. This bread is unique because it is made directly from the sprouted seed, which provides more vitamins, minerals, essential amino acids, and fiber. You get the whole-grain goodness without the flour! This type of bread is made from a sprouted wheat berry, picked, ground up, and then added to the mixture, which makes it “flourless." High in protein, vitamins and minerals, and packed with plenty of fat-fighting fiber, this is the perfect item to include in your menu plan!
Pair this with some grain-fed beef for a healthy steak sandwich, which packs plenty of nutrition and loads belly slashing fiber!
#1 Whey Protein
This widely used supplement is the byproduct of cheese manufacturing. The liquid left over is purified and made into whey powder, concentrated whey protein, or whey protein isolate. Whey powder is used in many products from bakery items to infant formula. Whey is power packed with essential amino acids, which are the building blocks for muscles. Research has shown only 56 grams of whey protein a day can help you lose weight without restricting your energy intake. This same research showed consuming whey protein resulted in a drop of 4 pounds, 1 inch off the waist, and a drop in body fat of 5 pounds!
Pair this together with ice, a tablespoon of peanut butter, and some fruit for a healthy and nutritious snack with plenty of appetite-suppressing protein and plenty of fat fighting potential.
Incorporating these five foods into a well-balanced diet plan will help provide essential nutrients needed to help you lose weight and keep it off. Fiber-rich foods have been shown to help curb your appetite which can suppress the desire to eating more. This will fight stubborn belly fat and help you stay healthy and fit for a long time to come!
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